Found 31 matching trials
Using Genetic Profile to Determine the Treatment for Patients With Ovarian Cancer Who Previously Received a PARP-inhibitor
PHASE2The purpose of this research study is to see how useful it is to look at bi...
Location
Princess Margaret Cancer Centre
Niraparib in Combination With Trastuzumab in Metastatic HER2+ Breast Cancer
PHASE1The human epidermal growth factor receptor 2 (HER2) regulates cell growth a...
Status
Active Not Recruiting
Location
University of Alabama at Birmingham
Japan Phase 2 Study of Niraparib in Participants With Advanced, Relapsed Ovarian Cancer
PHASE2The purpose of this study is to evaluate the safety and efficacy of nirapar...
Location
Aichi Cancer Center Hospital
Niraparib Efficacy in Patient With Unresectable Mesothelioma
PHASE2Multicentre, 2 arm, open-label UK randomised phase II trial to determine th...
Location
University Hospital Southampton, Southampton General Hospital
Niraparib in Combination with Cabozantinib (XL184) in Patients with Advanced Urothelial Cancer (NICARAGUA)
PHASE1Cabozantinib is an oral, small-molecule tyrosine kinase inhibitor. Its prim...
Location
Xarxa Assistencial Universitària de Manresa
SMMART Adaptive Clinical Treatment (ACT) Trial
EARLY_PHASE1SMMART-ACT is a feasibility pilot study to determine if testing samples fro...
Location
Multiple Locations
A Study of Niraparib in Patients With Ovarian Cancer in Clinical Practice
N/AThe main aim of this study is to check for side effects from treatment with...
Location
Takeda Selected Site
A Phase 1b/2 Trial Evaluating Safety and Efficacy of CAPecitabine in Combination With Ni-rapaRIb in HER2-negative Advanced Breast canCEr
PHASE1This study will be to combine oral capecitabine and oral niraparib such thz...
Location
Multiple Locations
Effects of Single Agent Niraparib and Niraparib Plus Programmed Cell Death-1 (PD-1) Inhibitors in Non-Small Cell Lung Cancer Participants
PHASE2This is a multicenter, open-label, phase 2 study to evaluate the efficacy a...
Location
GSK Investigational Site
Niraparib in Combination With Osimertinib in EGFR-Mutated Advanced Lung Cancer
PHASE1This research study is studying a combination of drugs as a possible treatm...
Location
Dana Farber Cancer Institute